Engineering decision-ready evidence
Evinexus is a clinician-led real-world evidence and digital twin consultancy. Our primary work supports sponsors building external control arm studies, evaluating single-arm trial designs, and engaging regulators on novel statistical methodologies.
External Control Arms & Digital Twins
Digital patient representations, synthetic data, and external control arms to optimize trials and support regulatory decisions.
Learn more about external control arms & digital twinsMethodology, study design, and data services
We support sponsors across the broader RWE workflow — from study design and patient profile curation through algorithm validation and data annotation. These services typically complement a digital twin engagement.
Medical Coding & Phenotype Definition
Expert medical code lists to define diagnoses, procedures, medications, laboratory tests, histology, and biomarkers for observational studies using healthcare claims, EHR/EMR, and registry data worldwide. Clinically curated, methodologically sound, aligned with regulatory, HTA, and publication standards.
Learn More→Algorithm Development & Validation
We develop and validate claims-based and EHR/EMR-based algorithms to accurately identify medical conditions and health outcomes for pharmacoepidemiology, epidemiology, comparative effectiveness research, HEOR, health outcomes research, drug safety, and pharmacovigilance. Built using clinically grounded logic and rigorous methodological standards ensuring accuracy, reproducibility, and regulatory readiness.
Learn More→Data Labeling & Annotation for AI & RWE
High-quality data labeling and clinical annotation to support AI, Generative AI, and RWE development using healthcare claims, registry, and EHR/EMR data. Enabling accurate model training, validation, and explainability for observational research and advanced analytics.
Learn More→Study Design, Analytics & Scientific Communication
End-to-end consulting and analytical services for RWE, comparative effectiveness research (CER), external control arms (ECA), and observational studies.
Learn More→Patient Profile Curation
High-quality data labeling and clinical annotation for longitudinal patient journeys using healthcare claims, registry, and EHR/EMR data. Supporting AI, GenAI, and RWE development with accurate model training, validation, and explainability.
Learn More→Have a trial that could benefit from a digital twin control arm?
We work most closely with VP-level clinical development and biostatistics teams designing single-arm or hybrid trials in rare and orphan oncology.
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